TL;DR
➡ Top medical alternatives to Minoxidil for treating hair loss are hair transplants, Finasteride, PRP injections, laser caps, and LLLT.
➡ Minoxidil’s alternatives do not have the same effect on stopping male pattern baldness. And the ones that do either have fewer studies or more prominent side effects.
➡ Some natural remedies and practices to use with or instead of Minoxidil are aloe vera, scalp massages, avocado oil, and rosemary oil.
In 2024, if you want a sustainable, long-term solution for minimizing or even wholly preventing hair loss, one of the best options you can resort to is Minoxidil.
However, being eligible to use Minoxidil is tricky. Unfortunately, not every patient who experiences baldness can benefit from Minoxidil, depending on how much their hair loss has progressed. Ultimately, some patients wonder if there are alternatives to this medication they can turn to instead.
In our clinic, we put the safety and comfort of every patient first, so we decided to give you your best and clinically proven options as alternatives for Minoxidil.
In this article, I will go through all of these options one by one, describe them, and explain how they are applied or how effective they are when we compare them to Minoxidil:
Table of Contents
Medical Treatments
Minoxidil is primarily a supplement medication for surgical procedures and treatments.
So, I will start by addressing your alternatives in this category:
1 – Hair Transplants
Usually, when a patient experiences hair loss, they are faced with two options based on how much their hair loss has progressed.
If a patient’s hair has just started to fall out recently, supporting medications such as Minoxidil are sufficient to slow down and completely prevent this process from progressing. But if hair loss has advanced enough to create balding areas or uneven hairlines, hair transplants become a viable option.
A hair transplant is a surgical process in which tissues containing hairs (called hair grafts) are extracted from one part of your scalp that still has hair, which we call the donor area, to be implanted into a balding area. The primary point of a hair transplant is that the patient requires some healthy and sufficient hair follicles left in their head to be implanted. In other words, the process focuses on treating bald areas with healthy areas that still have hair, so some amount of hair follicles (the roots from which your hair grows) are required.
Hair transplants contain different methods and varieties based on your scalp condition and preference, and they share a variable success rate compared to Minoxidil. According to a study, patients scored 7.8 on a Likert-like scale of 0 to 10 for their healing status and overall satisfaction. And this study only contained the FUE technique of hair transplant, an older version of hair transplants.
Still, a hair transplant alone does not guarantee you will not experience further hair loss from other parts of your scalp in the future.
So, to achieve great-looking and sustainable hair, you shouldn’t rely on any option alone.
UnitedCare’s approach
At UnitedCare, we focus on the best option available for you. And to do that, we suggest using Minoxidil before and after a hair transplant. As studies show, combining these options increases the success rate of a hair transplant and ensures that you will not experience any further hair loss.
Deciding on a medical option that will affect your future can be difficult, so we provide consultation to you and all our patients with all the modern hair transplant methods available.
Our difference is that for any of your preferences, each of the latest techniques and equipment are available, with all clinically proven supporting medications to offer after a transplant, provided by an experienced team of surgeons and professional dermatologists at an affordable price for your budget.
2 – Laser Caps
Sometimes, patients prefer an option with less contact, which does not contain a chemical or a needle. Laser caps are one of those options that start to shine.
With a self-explanatory name, laser caps are wearable caps/hats with a layer of laser diodes on their inner surface. These laser diodes work by projecting light into your scalp. Therefore, they are typically considered the home-use version of low-level laser therapy due to their convenience and lower cost.
Although the principles for how they work look like a work of science fiction, their structure is relatively straightforward and effective. Each laser diode shoots a red light containing a high amount of photons to your scalp, which is then absorbed by your cells and converted into a form of energy that supports cell regeneration and hair growth. So, it doesn’t directly promote hair growth but strengthens the cells responsible for it.
According to its most famous publisher’s website, these caps must be used for 30 minutes daily for 6 to 12 months to create sustaining results. As for their effectiveness and side effects, they contain the same pros and cons that traditional laser therapy methods have:
3 – Laser therapy / Low-level laser treatment
Unlike its recent invention, laser caps, the technology behind the laser therapy technique has an extensive background. Low-level laser therapy (LLLT) first appeared in the 1960s, thanks to the Hungarian physician Endre Mester. As a test, Dr. Mester projected low-level lasers on shaved mice. Then, he noticed that these test subjects showed much faster hair growth with laser projection than those without it. Lastly, in 2007, low-level laser therapy gained approval as a safe treatment for pattern balding. Since then, this method has been adopted by many clinics due to its effectiveness in promoting hair growth.
Due to their effectiveness, traditional laser therapies are more costly than many other hair loss options. They are also safer since they do not directly engage with the patient’s body. For LLLT to work, it requires the constant attention of several weekly sessions for an extended period.
Still, many patients see this option as viable despite its cost and the long time required to show results because it is very effective in battling hair loss and shows no significant side effects, according to studies.
4 – Stem Cell Treatment
Stem cell treatment is among the latest developments in the hair restoration field.
The treatment uses the beneficial parts we call stem cells, which are your body’s own hair follicles.
🔵 First, we collect stem cells from your blood via a harvesting system. Then, we inject the same cells back into the balding areas of your scalp.
The injections are done with FDA-approved and CE-certified Regenera Activa AMT stem cell kits and centrifuge, which are strong supporters of the treatment’s effectiveness, as studies show:
According to a 2017 study, a 29% increase in hair density was observed in the treatment zone (compared to 1% in the control zone) 23 weeks after the stem cell autologous micro-graft transplants.
Also, other than density, stem cells help slow down the loss of hair and promote new hair growth by strengthening your hair follicles. That’s why they are especially preferred in the early stages of hair loss.
5 – PRP Treatment
Platelet-Rich Plasma (PRP) is a type of healing technique in which a patient’s body is a part of the healing process. First, a low amount of the patient’s blood is drawn from their body, and then the platelets in their blood are separated to be later injected into their scalp.
In other words, this treatment does not contain any external source of chemicals to be injected.
Although this treatment has only been used for hair loss in the last two decades, its history goes back to the 1970s. In its early times, this medication was used by hematologists to treat blood disorders. However, when orthopedists started using PRP’s healing and growth factors for treating sports injuries in athletes, it attracted the media’s attention to become more widespread. The most obvious proof of PRP’s effectiveness was the improved recovery time in well-known athletes of the time, which led to the beginning of studies about it.
Existing studies show promising progress in the effectiveness of PRP treatment for treating hair loss. However, the downside of this method is that an expert dermatologist is needed for the surgery’s long injection process. Although this is an FDA-approved method, it also comes with specific side effects such as pain, bleeding and burning around the injected area, scalp numbness, and infections.
That is why we suggest that every patient considering a PRP treatment should consult with a clinic that has an expert dermatologist on their staff.
Medications
Minoxidil’s most prominent use is treating hair loss as a medication, which it does under its brand name, Rogaine.
So, I will also go through all your alternatives that are usable medications:
6 – Finasteride
As an FDA-approved supplement medication for MPB, Finasteride is one of the most prominent alternative medications to Minoxidil. Usually appearing under its brand name, Propecia, it is a topical oral medication you can get with your doctor’s prescription.
Finasteride is an inhibitor drug that slows down or reverts hair loss by preventing the production of the hair loss hormone DHT. Its effectiveness in this process is incredibly high, as studies show that it has a rate of showing hair growth in 66% of patients and altogether preventing further hair loss in 83% of patients.
The downside of this medication is that it is not a one-time solution, but more importantly, it has some side effects. Although they are scarce, temporary, and curable, they still raise concerns. These side effects include rash, erectile dysfunction, and ejaculation disorder.
7 – Saw Palmetto
Saw palmetto is the most recent alternative method we have today for treating hair loss. Although Saw palmetto berries have been used in American folk medicine for several hundred years to treat prostate problems, their history in treating hair loss and becoming a registered medication is pretty new. It appears on our list because of the discoveries made since the 1900s about its effectiveness in treating MPB.
The name of this medication belongs to its main natural ingredient, a flowering plant called saw palmetto. Saw palmetto plant works by blocking the conversion of testosterone into the DHT hormone (dihydrotestosterone, the primary hormone responsible for hair loss), similar to inhibitor medications.
Similarly, this method must be used continuously for a long time to show and maintain its benefits. And, as this medication is more pure and natural in its form, modern studies show little to no side effects whatsoever while demonstrating its effectiveness.
Aside from its topical medication form, you can also consume this plant in the form of tea. However, this is where its downsides begin to appear. Since saw palmetto is a very pure form of hair loss medication, its required dosage is incredibly high compared to Minoxidil. Whether it is a food supplement or not, around 200 mg of its dose must be used several times a day.
As for its effectiveness, studies show that 38% of patients who took 320 mg of saw palmetto every day for two years showed improvement in their hair loss, compared to Minoxidil’s effectiveness of 62%.
8 – Procapil
Continuing from the list of medications that contain natural ingredients, Procapil is another noteworthy example. It is a unique mixture of various natural ingredients in a single medicine specially produced to help with hair loss.
This medication is another inhibition drug as it blocks the production of the DHT hormone to stop hair loss. As for its usage, this medication appears in two different forms: Either as a topical solution for male pattern baldness or as an oral that you can take daily, which will require your continuous dedication.
As for its effectiveness, a study shows that the objective success rate for preventing hair loss and subjective satisfaction rate from patients was much higher than Minoxidil (almost two times).
The downside is that Procapil’s potential side effects are much more striking in comparison. These side effects include nausea, vomiting, stomach upset, rash/itching, or headache.
9 – Viviscal
Unlike its alternatives for treating hair loss in medical terms, Viviscal works without directly interacting with your DHT hormones. That is precisely why this drug is called a dietary supplement for hair growth.
The way it works is by supporting your existing hair with nutritious proteins. Typically, your hair constantly renews itself over time by dropping your old hair and regrowing it new. When Viviscal comes into play, it brings rich amounts of protein into your strands, encouraging new ones to grow.
As seen in multiple studies that are even accessible on its website, Viviscal is an excellent tool for hair loss, especially if an increase in hair diameter and thickness is the primary objective. Although it cannot get approval from the FDA for not being a drug, its clinically proven factors make this medication “fitting” for the FDA requirements.
This medication comes in the form of either a liquid or a powder. As the former version contains many high-quality ingredients, we heavily suggest getting the liquid version to get the most benefit possible from this method.
The usual reason that some patients prefer not to choose this method is that it is still not approved by big medical institutions such as the FDA.
10 – Spironolactone
Usually appearing under the brand name Aldactone, Spironolactone is an FDA-approved water pill that is a regulating and diuretic medication.
Due to its effects, it is generally prescribed to help patients with high blood pressure or low potassium levels by reducing the absorbed levels of salt to keep the potassium levels high.
However, modern research has found more uses for its regulating effect, such as treating androgenetic alopecia.
In a 2023 study, the topical version of Spironolactone was prescribed to 618 patients (65 men, 553 women) of different ages (approximately 20 patients for almost every age).
👉 The study concluded that the use of Spironolactone is both an effective and safe treatment of AGA, which helps by enhancing the effectiveness of any conventional treatments, such as Minoxidil.
However, in terms of being an alternative, the study especially says that the newer topical version is so much safer than the oral version that it can even become an alternative to Minoxidil altogether.
Still, the studies depicting this medication’s success are still relatively low in numbers and require more in-depth research.
11 – Prostaglandin
Prostaglandin is a new, clinically proven method that takes its name from the molecules used in the process.
Prostaglandins are naturally occurring molecules found in almost every cell in our bodies, and they can affect many conditions, including hair loss. They are produced by the adipose tissues, the same cells responsible for creating new hairs. In other words, prostaglandins work by boosting your body to make more, better, and thicker hair.
These medications typically come in an injection form, where they are first injected into your scalp before being absorbed into your bloodstream. They then cause your body to start producing more of the beneficial prostaglandin cells naturally through enzymes, boosting your body’s existing production cycle.
Studies about its effectiveness show that this medication dramatically speeds up the regeneration process of hair follicles, which in turn causes your hair to grow faster. But its efficacy falls behind Minoxidil.
In summary, Minoxidil has many alternatives with different benefits and downsides. However, all the methods I have gone through are medical options, such as surgical or drugs. In other words, they contain chemicals modified in a lab.
Combined with their potential specific side effects, regardless of how rare they might seem, some patients see these methods as no different than Minoxidil and instead look for natural alternatives.
So, here are your best natural alternatives for Minoxidil that are proven to work and are approved by clinics for continuous usage:
Natural Alternatives to Minoxidil
12 – Aloe Vera
⚠️ One thing we should mention first is that Aloe Vera, like many other natural alternative methods, contains the possibility of triggering your sensitivity or allergy to the medication (due to the vast number of acids in it) if you have one. As always, our motto is that you should advise your doctor about your medical history beforehand.
Studies show that Aloe Vera is a plant with many beneficial acids, enzymes, minerals, and vitamins that can positively affect your hair’s health.
The beneficial compounds in Aloe Vera bring out this natural medication’s effectiveness in two ways:
1️⃣ The first is that vitamins and acids feed your scalp to enhance your hair’s health for regrowing faster, thicker, and more resistant.
2️⃣ The second is that other ingredients, such as enzymes and minerals, help you by preventing you from having an oily scalp and reducing the inflammation in your scalp. These are known reasons for slowing down and obstructing hair loss.
Due to these active ingredients, this natural remedy has been a trusted option for hundreds of years. To explain how to use it, you can apply aloe vera gel directly on your scalp by massaging it gently twice a day for about 10 minutes.
💡 The last thing to remember about this medication (and every other one in this final part of the list as natural remedies) is that due to its less chemically-enhanced background, its effectivity is less than other medical alternatives.
Therefore, they usually appear as supportive medications that you should use alongside different methods for better results.
13 – Scalp Massages
Scalp massages are one of the most popular and proven methods to stimulate hair regrowth.
In support of your hair’s regrowth, this remedy increases your scalp’s health in two ways:
- Scalp massages stretch the cells of hair follicles and make them thicker, resulting in thicker hair produced from your hair follicles. According to a study, doing scalp massages for 4 minutes per day for 24 weeks increases hair thickness by %10.
- Applying scalp massages improves the overall blood circulation throughout your scalp, boosting your hair growth. A study showed that hair loss stabilization and increased regrowth were reported in 69% of 340 patients who have done scalp massages of 10 to 20 minutes twice a day for six months.
This method is quite simple; you can gently massage your scalp using a massage brush or your hands. Applying light pressure to the skin for 5 to 10 minutes per day should be enough. Just make sure that you thoroughly wash your hair, hands, or brush beforehand.
14 – Avocado Oil
Many famous and trusted natural remedies for treating hair loss are natural oils. Because their rich ingredients usually contain a high amount of effective compounds, enough to attract researchers’ attention.
Most of the time, they are applied with the support of scalp massages, which also heavily promote your hair growth.
This method’s history of trusted use goes back to the Aztecs’ time for promoting hair growth and preventing hair loss. That is because Avocado oil is rich in vitamins such as A, B1, B2, D, and E. All these vitamins greatly help your body nourish your hair’s roots.
It also contains a good amount of very beneficial acids, biotin, and antioxidants.
These are excellent sources for strengthening your follicles’ health and reducing hair loss.
To benefit from its positive effects, you can apply half a teaspoon of Avocado oil directly on your scalp three times a week before washing it off with shampoo after approximately 10 minutes. Recent studies also show that aside from treating the setbacks of natural hair loss, this method is also helpful in treating damage to your hair caused by outside sources.
15 – Coconut Oil
Coconut oil is another efficient natural oil remedy for hair loss.
It has three benefits in keeping your hair’s health in check:
1️⃣ Its effectiveness primarily comes from containing 50% Lauric Acid, which has been found to be very effective in combating yeast that can build up on your scalp, which creates dandruff formation and leads to hair thinning.
2️⃣ Additionally, lauric acid also penetrates the hair shaft and reduces keratin loss.
3️⃣ Lastly, it also acts as a natural antioxidant and protects against free radical damage that causes premature aging and hair loss, as we’ve mentioned in the causes of hair loss article.
⚠️ As a small reminder, you should apply coconut oil to your scalp after your hair is washed for optimal results. It will prevent protein loss. (Keep in mind that keratin is also a protein that makes up your hair, skin, and nails.)
16 – Geranium Oil
Geranium oil is another home remedy used for many decades to stimulate hair growth in balding patients. However, its clinically proven background is pretty new.
Despite that, these studies still show successful results.
According to a study conducted in 2017, its effectiveness at significantly enhancing hair regrowth and preventing hair loss is comparable to that of Minoxidil.
This medication regulates the amount of dryness on your scalp and around your hair follicles by using its beneficial chemical compounds. Therefore, using them regularly allows your hair follicles to work healthier.
To benefit from it, you can apply Geranium oil directly on your scalp 3 or 4 times a week for about 5 minutes before washing it off with shampoo.
17 – Rosemary Oil
The oil in this herb is a widespread, universally known beneficial remedy that has been used for many different conditions over the years, including MPB.
This remedy’s beneficial effects come from affecting the insides of your scalp.
By using the ingredients in it, such as specific acidic chemicals like Carnosic acid, Rosemary oil increases the blood flow around your head. As a result, your hair follicles get more oxygen and nutrients pumped into them. And when your hair follicles absorb more nutrients from your bloodstream into their cells, your hair starts growing healthier.
Aside from taking the established place of Rosemary essential oil in different cultures worldwide as evidence, clinical studies have also shown its effectiveness.
According to an interesting study, Rosemary oil was as effective as Minoxidil in treating hair loss. In this research group, the rate of increase in hair count was the same for both groups using Minoxidil and Rosemary oil at the end of the study.
More importantly, in contrast to and unlike Minoxidil, Rosemary oil has almost no side effects, such as scalp sensitivities or irritations.
You can apply this remedy on your scalp 3 to 4 times a week for about 10 minutes after showering.
18 – Fatty Acids
The most recognizable mutual part of natural remedies for hair loss is that the working principle for almost all of them is strengthening your hair follicles or scalp to increase their health, reflecting positively on your hair growth.
And when we talk about nutritious natural medications for hair growth, the most irreplaceable and important one is, without a doubt, fatty acids.
Fatty acids usually refer to two essential nutrients: Omega-3 (found in fish) and Omega-6 (found in most nuts, seeds, and oils like sunflower or canola). Both of these acids are proven to help induce hair growth by studies showing that fatty acids increase hair density in patients by 62%.
These beneficial nutrients create a protective barrier on your scalp’s skin and prevent dryness or itchiness. As a result, your hair follicles get the chance to work healthier without being affected by outside resources or harmful chemicals such as DHT.
You can gain the benefits of fatty acids in different ways:
- You can apply them on your scalp 3 to 5 times a week for about 10 minutes.
- You can eat them rather than putting them on your scalp, which allows your body to absorb these nutrients better. So, you can instead take fatty acid supplements such as daily capsules to benefit from these as much as possible.
19 – Onion Extract
⚠️ Reminder that raw onion juice is very acidic and can harm your scalp and hair. Therefore, we suggest you use products such as shampoo that contain this natural ingredient instead.
Thanks to its easy access and practical use, onion extract has been among the most used natural methods for treating hair loss since ancient times. It is a reliable remedy because onion contains many good properties that directly affect your hair’s health, such as amino acids, vitamins, enzymes, magnesium, and even keratin.
👉 Speaking of keratin, all these ingredients are so effective that they have their own products; however, onion extract contains them all at once under its juice, which heavily promotes hair growth, as supported by studies.
Although studies show that onion extract thoroughly supports hair density and increases hair growth, using it directly on your scalp (instead of consuming it) is heavily dangerous and harmful due to its acidic nature. Therefore, we suggest certain products, such as onion extract-containing shampoo.
💡 According to a study, this shampoo product nourishes hair follicles, promotes hair growth, and prevents dryness by moisturizing the scalp. If you plan on using this shampoo, the same study suggests applying it to your scalp and keeping it there for 5 minutes before washing it off for the best results.
20 – Adapting to a better lifestyle
In the daily life of our modern era, our lives are so crowded with responsibilities and constant rushing that we hardly show any effort to spare time for a proper diet and exercise. Consequently, we look for shortcuts such as pills, medications, and natural remedies that we can take on the go.
So, when we take these into notice, the most natural and impactful alternative for any clinical medication is ensuring that you never need them by maintaining a stress-free lifestyle with a balanced diet and a proper exercise routine. Therefore, we suggest you consider the benefits of diet and exercise.
➡️ Avoiding nutrition deficiencies or extreme levels that create toxicity and trigger hair loss are among the few obvious benefits. In 21st-century medicine, the Mediterranean diet is one effective technique we advise our patients. According to a study, it consists of high proteins, raw vegetables, and fresh herbs, which highly contribute to its effectiveness in reducing the risk of hair loss. With this diet, you should try to consume raw vegetables and fresh herbs at least three times a week to see the results of this diet.
➡️ The most apparent benefit of exercising is avoiding low blood circulation in your scalp. Movement and stimulation with exercise increase the amount of blood circulation in your scalp, which turns into more oxygen and nutrition flow going to your hair follicles. Besides, physical stress with exercise can significantly reduce mental stress by giving your body a chance to release tension.
➡️ Speaking of stress, you can avoid it with an orderly lifestyle. According to a study, researchers have found a direct link between hair loss and stress levels, as high amounts of continuous pressure from non-released stress increase hair loss.
We know that it is not easy to make changes in a single day. Therefore, we suggest making small changes over time. When you see the benefits appearing over time, you can continue making minor changes to maintain this lifestyle.
So, what should you choose?
Honestly, there is no definitive answer to the best alternative to Minoxidil. In every possible sense, your body and your hair are unique to you. So, we suggest getting advice from an expert, especially a dermatologist, on which options would best suit you, depending on your medical background.
And that is why we are here.
At UnitedCare, we begin your hair transplant process by offering you a free one-on-one consultation with our expert doctors to determine your suitability.
💊 If so, our holistic approach provides advanced technologies and bio-enhancements to ensure you do not need another surgery.
Once you have decided on a method, we begin the treatment with the utmost attention. 💉
But most importantly, we stay in contact with our patients even long after the surgery, ensuring that your transplant becomes permanent. 🍀
Affordable hair transplant costs, a holistic approach, and experienced dermatologists on-site are here to provide you with the right solution.
Ready to begin the journey? Click here to reach out for a FREE consultation:
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Frequently Asked Questions (FAQs)
What is a good substitute for Minoxidil?
Minoxidil contains many natural or medical alternatives. In terms of medical options, depending on how much your hair loss has progressed, Finasteride or hair transplants can be a perfect method. Alternatively, many natural alternatives, such as geranium or rosemary oil, are present. However, none of these options is a clear substitute for Minoxidil. They all work differently and have different benefits and downsides, just like Minoxidil. Ultimately, your safest and most effective option is to combine these methods with the guidance of an expert dermatologist in a clinic.
Is there a safer alternative to Minoxidil?
It depends. If you are talking about alternatives with less prominent side effects, there are medical options such as saw palmetto. If you are talking about a completely natural choice, then there are options such as aloe vera and onion extract shampoo. However, choosing an alternative with fewer side effects or that is entirely natural does not guarantee that there will not be any risks. And more importantly, it does not guarantee that these options will be as effective as Minoxidil. You should consult with your doctor, and based on your medical history, choose which options to use and combine for the best results in preventing hair loss.
How can I regrow hair without Minoxidil?
If your baldness is in its early stages, you can use Minoxidil alternatives such as Procapil or avocado oil. However, if one area in your scalp has wholly lost its follicles due to extreme balding, you might want to apply for stronger resolves, such as getting a hair transplant, as regrowing hair may not be possible. In that case, your hair will start regaining after being transplanted in the recipient area, but the rest of your scalp will still be at risk. So, seeking further protection from hair regrowth medications would be best.
Can I stop Minoxidil and switch to an alternative?
Yes, like many other hair loss medication options, Minoxidil is not a one-time treatment. So, its benefits and potential side effects only occur if you use the medication on a regular basis. In other words, if you stop using the medication, its effects on your body will fade away, and you shouldn’t have any problem with switching to an alternative. Still, getting a consultation with your doctor beforehand is the safest option.